Allaes NAC plus glycine

Overcome stress and inflammation: How NAC + glycine supports your health

NAC (N-acetylcysteine) is an amino acid known for its powerful antioxidant properties. It helps the body fight harmful substances that can damage cells. NAC also supports detoxification, promotes lung health, and has shown benefits in conditions related to the respiratory system. Interestingly, it's also being explored for improving fertility — one of its newer and promising applications.

Glycine, on the other hand, helps calm the mind and body. This amino acid supports restful sleep, reduces stress and anxiety, and improves focus and memory. It also plays an important role in physical recovery, making it valuable for both mental and physical well-being.

When NAC and glycine are combined, their effects are amplified. One of their most important roles is boosting glutathione levels in the body. Glutathione is a key antioxidant that protects cells from damage and supports overall health. It's especially important for liver function, as it helps eliminate toxins and improves metabolic balance.

Together, NAC + glycine is a powerful combination that helps your body combat oxidative stress, recover from physical and emotional strain, and stay healthy at the cellular level.

Who can benefit from NAC + glycine?

✔ If you want to slow aging and stay physically active – NAC + glycine may help improve muscle strength, walking speed, and endurance. Studies show these compounds support DNA protection and may slow aging processes. In older adults, they’ve been linked to better blood pressure and overall physical performance [6].

✔ If you’re looking to increase your antioxidant defense – This combo raises glutathione levels, one of the body’s most powerful antioxidants. Glutathione helps reduce oxidative stress and inflammation, protecting your cells from damage — especially important with age or chronic illness [1][2]. Oxidative stress happens when unstable molecules (free radicals) damage your cells. Antioxidants like glutathione neutralize them, helping your body stay healthy.

✔ If you have metabolic issues or insulin resistance – NAC + glycine support mitochondrial function and help your body burn fat more efficiently. Mitochondria are the energy centers of your cells — the better they work, the more energy your body has. This can be beneficial for people with type 2 diabetes, obesity, or those doing endurance training like running or CrossFit [2].

✔ If you want to improve focus and brain performance – These amino acids may support memory, concentration, and cognitive function, especially in older adults. They’ve been shown to help with age-related changes in brain health and attention [3][5].

✔ If you need to support your liver and immune system – NAC plays a key role in liver detox and immune regulation. It helps clear out toxins and supports your body’s defenses, which is especially important under stress or illness [4].

✔ If you care about heart and blood vessel health – NAC may help regulate cholesterol and reduce the risk of atherosclerosis, supporting cardiovascular health — crucial for those at risk of heart disease [8].

✔ If you’re recovering from illness or intense training – NAC + glycine promote tissue recovery, reduce inflammation, and help your body bounce back faster. This makes the combo helpful for athletes and anyone recovering from illness or injury [9].

✔ If you have skin problems – NAC may help reduce skin inflammation, making it beneficial for acne-prone or inflamed skin conditions [10].

✔ If you’re dealing with stress or poor sleep – Glycine supports the nervous system, helping you relax, fall asleep more easily, and reduce stress levels. Ideal for people under pressure or those who struggle with sleep [11].

How to take NAC + glycine correctly?

• Recommended dosage: Most people start with 2–4 capsules per day. Depending on your health needs — for example, liver support — the dose can be increased to 6–8 capsules daily.
• Best time to take: It's ideal to take NAC + glycine in the morning, either before or after food.
• How long to take: NAC and glycine work cumulatively, meaning their benefits build up over time. A minimum of 3–4 weeks is recommended to notice results. For longer-lasting benefits and to maintain optimal glutathione levels, many choose to continue supplementation for several months.

How does NAC + glycine work?

NAC (N-acetylcysteine) and glycine are two essential building blocks for producing glutathione — one of the body’s most powerful antioxidants. Glutathione plays a central role in protecting cells from damage caused by oxidative stress and supports many important biochemical processes.

Oxidative stress occurs when harmful molecules called free radicals build up in the body and begin to damage cells. To neutralize these radicals, the body needs antioxidants — and glutathione is one of the most effective. It helps detoxify harmful substances, supports the immune system, and regenerates vitamins C and E, both of which are also antioxidants.

The challenge is that glutathione itself can’t easily enter cells from the bloodstream due to its large molecular size. However, NAC and glycine are small and easily absorbed, allowing your body to produce glutathione directly inside the cells — where it’s needed most.

Taking NAC and glycine gives your body the raw materials it needs to keep glutathione levels up — which is especially helpful during periods of stress, heavy training, or as you get older, when your cells are more vulnerable to damage.

They also support the work of mitochondria — the parts of your cells that produce energy. When your mitochondria function well, your cells stay healthier for longer. That’s why NAC + glycine can be especially helpful for people who stay active or want to maintain their health as they age.

Composition matters!

Combining NAC with glycine is one of the most effective ways to raise glutathione levels in the body — that’s exactly why we built our formula around these two components. Taking NAC alone may not give optimal results, since glycine is a critical part of the glutathione molecule.

NAC is a source of cysteine — one of the three amino acids needed to make glutathione. Cysteine is considered the “rate-limiting” amino acid, meaning your body can’t produce enough glutathione without it. The other two required amino acids are glutamate and glycine. Glycine plays a key structural role in the glutathione molecule and is essential for its full synthesis.

Without enough glycine, the body may not be able to complete glutathione production. Even if you're supplementing with NAC and increasing cysteine levels, low glycine can still hold the process back. Taking both together supports more efficient glutathione synthesis directly inside the cells.

Glycine also improves NAC’s bioavailability. It helps the body use cysteine more efficiently by activating the enzymes involved in glutathione production and supporting better uptake of cysteine into cells.

Benefits for PEDs Users

For those using PEDs, intense training and liver strain are major stressors on the body. These factors increase the risk of chronic inflammation and weaken the immune system — an effect that’s often worsened by androgens and anabolic steroids. Regular supplementation with NAC + glycine can play an important role in minimizing these side effects and supporting overall recovery and resilience.

Cell-protective and antioxidant-supporting compounds like NAC and glycine are essential not only for daily performance, but also for long-term health. While direct clinical evidence on lifespan is limited, maintaining cellular integrity and reducing inflammation are key processes that support healthy aging — especially in athletes under high physical and pharmacological stress.

Notably, studies have shown that taking NAC before high-intensity efforts such as sprinting can improve repeated sprint performance, making it a valuable tool for athletes focused on endurance and peak output [7].

Additionally, this combination acts as a potent immune modulator — something especially critical during heavy training blocks. When the immune system is suppressed from overtraining, NAC + glycine helps lower the risk of illness and supports immune balance. This makes it a smart choice for those pushing for maximum performance without compromising long-term health.

References

[1] Glutathione deficiency and oxidative stress in the elderly

[2] N-acetylcysteine and glycine improve mitochondrial function

[3] Glycine treatment improves memory in elderly subjects

[4] Glutathione deficiency in the epithelial lining fluid of the lower respiratory tract in idiopathic pulmonary fibrosis

[5] Efficacy of Glycine and N-Acetylcysteine Supplementation on Glutathione Redox Status and Oxidative Damage

[6] N-acetylcysteine and glycine increases length of life

[7] Effect of N-acetylcysteine on cycling performance after intensified training

[8] N-acetylcysteine: cardiovascular and metabolic benefits

[9] The Antioxidant Role of Glutathione and N-Acetyl-Cysteine Supplements and Exercise-Induced Oxidative Stress

[10] NAC and skin inflammatory disorders

[11] Glycine improves sleep quality in humans