Pitavastatin 1 mg tab

• Composition: Pitavastatin 1 mg
• Category: Cycle support (statin)
• Purpose: Correction of lipid profile, reduction of LDL, support of HDL, prevention of cardiovascular complications
• Form: Tablets
• Administration: Oral

What is Pitavastatin?

Pitavostatin is a statin drug that lowers low-density lipoprotein (LDL) levels and improves overall lipid balance (HDL). Its main advantage over other statins is that it does not increase blood glucose levels, making it one of the safest medications for long-term use.

It is excellent as a cycle support during anabolic steroid cycles, which cause an increase in LDL and a decrease in HDL, which elevates the risk of heart diseases if left untreated. Thus, Pitavastatin stands out as a safe, effective, and low-cost option.

Main effects of Pitavastatin

🔽 Lowering LDL cholesterol

❤️ Increasing and maintaining HDL cholesterol

📉 Lowering triglyceride levels

🛡️ Reducing the risk of atherosclerosis and other cardiovascular complications

🫀 Maintaining vascular health during high exercise and exercise

🍬 Neutralizing effect on glucose levels (other statins can increase blood sugar and reduce insulin resistance)

How to take pitavastatin?

Dosage of Pitavastatin and administration schedule

Starting dosage: 1 mg once daily.

Increase dosage gradually to a maximum of 4 mg per day (if lipid profile still shows high LDL levels).

Dosage schedule: once daily, at the same time, regardless of food intake.

Duration of use when used in a cycle with AAS: throughout the entire cycle and for an additional 4-6 weeks afterward to minimize risks.

Discontinue use when lipid profile results are good and stable(LDL has been reduced to normal levels).

✅ For best results, it can be taken with Ezetimibe. Ezetimibe blocks intestinal cholesterol absorption, and when combined with Pitavostatin, LDL reduction is significantly more effective than monotherapy. Approximate dosages:

• Pitavostatin 1 mg
• Ezetimibe 10 mg
• Once daily at the same time

Important to note

• It is advisable to avoid alcohol due to the risk of excessive liver stress.
• Avoid taking this medication with certain antibiotics and antifungals due to the risk of side effects such as muscle pain or liver stress.
• The medication can disrupt the energy balance in muscle cells and affect mitochondrial function, so we recommend testing creatine kinase levels to monitor for possible muscle damage.
• Have a lipid profile and liver enzymes tested to assess the medication's effect.
• If severe muscle pain, weakness, or dark urine occurs, discontinue use immediately and get tested.

Side effects

• Headaches.
• Mild nausea or gastrointestinal symptoms.
• Fatigue and weakness.
• Rarely, muscle pain or cramps. This side effect is related to the fact that statins can disrupt the energy balance in muscle cells and affect mitochondrial function. In severe cases, this can lead to elevated creatine kinase levels, so it's important to monitor your creatine kinase levels if symptoms appear.

How to store Pitavastatin?

• Store in a dry place at room temperature.
• Store in a dark place away from sunlight.
• Keep out of reach of children.

How does Pitavastatin work?

Our liver requires cholesterol; it's a building block for the production of bile acids (which help digest fats), steroid hormones, and vitamin D.

• LDL transports cholesterol from the liver to tissues, and in excess, it can deposit on the walls of blood vessels.
• HDL, on the other hand, removes excess cholesterol from tissues and blood vessels and returns it to the liver for processing.

PEDs and especially AAS increase LDL levels and decrease HDL levels, so liver and heart support are always necessary along with a steroid cycle.

Inhibition of cholesterol synthesis and Increase of LDL receptors

Pitavostatin blocks the enzyme HMG-CoA reductase in the liver, which is essential for cholesterol production. When this enzyme is temporarily inhibited, the liver produces less cholesterol, and the body begins to actively remove it from the blood.

When total cholesterol levels drop, liver cells develop cholesterol-capturing traps on their surface called LDL receptors. LDL typically transports cholesterol from the liver to tissues, but when it becomes too high, the liver begins to actively reabsorb LDL particles from the blood using special receptors, thereby reducing LDL levels and the risk of cholesterol deposits on artery walls.

(Taguchi et al., 2018, Yokote et al., 2011, Adams et al., 2020)

Additional effects of Pitavastatin

In addition to its effects on cholesterol, Pitavastatin influences many other factors.

For example, Pitavastatin reduces the activity of immune cells in blood vessel walls and also reduces the production of inflammatory molecules (C-reactive protein, etc.), thereby reducing arterial wall irritation and chronic inflammation in general (Yoshika et al., 2010).

Antioxidant activity protects tissue from damage, improves blood flow, and prevents thrombus formation (Inamoto et al., 2010). At the same time, the function of the endothelium (the inner lining of blood vessels) improves, regulating vascular tone and the production of nitric oxide, which helps blood vessels dilate while reducing pressure (Takase et al., 2013).

Studies also show that Pitavostatin may support cognitive function (Kurata et al., 2011), reduce the risk of dementia (Filho et al., 2025), have positive effects on bones (Majima et al., 2007) and gut microbiota (Dias et al., 2020).

FAQ

How long does it take for Pitavastatin to work?

The first changes in the lipid profile can be noticed within the first 2 weeks, but a noticeable decrease in LDL levels is observed after 4-6 weeks of regular use.

Is Pitavastatin hydrophilic or lipophilic?

Pitavastatin is a lipophilic statin, meaning it penetrates cells better.

Does Pitavastatin influence hormone balance or testosterone levels?

Pitavostatin has a neutral effect on testosterone and other hormone levels, making it a better alternative than other statins and at a reasonable price.

Is Pitavastatin better than Rosuvastatin?

Although Rosuvastatin may lower LDL more effectively, it is much more likely to increase blood sugar and insulin resistance, making Pitavastatin a much better and safer alternative.

Does Pitavastatin cause weight loss?

It doesn't directly cause weight loss. It improves lipid profiles and protects the cardiovascular system, which can also be weakened by excess weight and body fat.