• Composition: human chorionic gonadotropin (HCG), 5000 IU.
• Category: peptide, cycle support.
• Purpose: stimulation of gonadal function, maintenance of endogenous testosterone production, recovery of reproductive function.
• Form: vial with lyophilized powder + 1 ml ampoule of injection water for reconstitution.
• Administration: subcutaneous injections.

What is Human chorionic gonadotropin?

Human chorionic gonadotropin (HCG) is a hormone naturally produced in the body during pregnancy, but is also necessary for professional athletes during anabolic steroid cycles to restore natural testosterone production, which is suppressed during AAS use.

It mimics the action of luteinizing hormone (LH) and was originally used medically to stimulate testosterone production and spermatogenesis in men and to induce ovulation in women.

Main effects

📈 Increases and maintains natural testosterone levels.

🧬 Helps restore and improve fertility and libido.

⚙️ Activates testicular function, preventing their shrinkage and loss of function due to steroid use.

🔁 Restores hormonal balance during an AAS cycle.

How to take HCG?

Before buying HCG online, be sure to read the instructions and precautions.

You can read about how to dilute the peptide and make injections in this instruction.

Dosage and administration schedule

⚠️ HCG should be included in any course that lasts more than 6 weeks!

Be sure to get your levels of testosterone, LH, FSH, and estradiol tested before, during, and after the course, so you can adjust your dosages if necessary and ensure you've completed the course correctly.

Precautions

• Do not combine with drugs that increase estrogen sensitivity (e.g., selective estrogen receptor modulators — clomiphene, tamoxifen, etc. These drugs will be used for PCT after the main steroid cycle with HCG is completed).
• Do not combine with other gonadotropins or anabolic steroids that mimic LH, to avoid excessive stimulation.
• Monitor the following blood tests: total and free testosterone, LH, FSH, estradiol, prolactin, as well as β-HCG levels during long-term cycles.
• Monitor for signs of excess estrogen — edema, nipple sensitivity, decreased libido.
• Avoid concomitant use of strong antiestrogens unless there are clear signs of estrogenic activity, to avoid imbalance. Regularly monitor liver function and lipid profile during long-term use as part of a PCT or AAS course.
• Buy human chorionic gonadotropin only from trusted resellers. In our online store, you can find pharmaceutical-grade HCG and view laboratory test results.

Possible side effects

• Possible increase in estrogen levels (with excessive doses).
• Increased sensitivity or swelling of the testicles.
• Mood changes.
• Fatigue with abuse.

How to store?

• Store in a cool place (2–8 °C). If storing in the refrigerator, avoid storing it against a wall to prevent freezing, which will damage the peptide structure.
• Keep away from sunlight and heat.
• After reconstitution, the product can be stored for 1–2 months if all storage conditions are properly observed.

How does HCG work?

Human chorionic gonadotropin was first isolated from the urine of pregnant women, as this hormone supports the development of the corpus luteum and progesterone production in early pregnancy. In medicine, HCG was first used to stimulate ovulation in women and restore spermatogenesis in men, as it can substitute for the effects of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). Later, thanks to these properties, this medicine gained popularity in sports pharmacology as a means of supporting natural testosterone levels and preventing testicular atrophy associated with AAS use. That’s why it’s important to buy human chorionic gonadotropin (HCG) as part of any steroid cycle — it helps prevent hormonal imbalance and post-cycle complications.

HCG is a functional "doppelganger" of luteinizing hormone (LH): it binds to LH receptors on Leydig cells in the testes and triggers testosterone synthesis. It maintains intratesticular testosterone (ITT), and preserves testicular volume and function, which is important when using exogenous AAS that suppress the hypothalamic-pituitary-gonadal (HPG) axis.

Why is it necessary to use HCG in >6 weeks AAS cycles?

With long-term use of anabolic steroids:

The pituitary gland decreases LH/FSH secretion → Intratesticular testosterone levels fall → Testicular atrophy and loss of function.

Administering it during the fourth week of the cycle helps maintain testicular activity and prevent atrophy. This medication is important not only for maintaining testicular function, but also for maintaining overall hormonal balance. By supporting natural testosterone production, the body maintains the balance of estradiol and DHT, an imbalance that can cause problems with libido, mood, and energy levels.

Important: HCG is a testicular stimulant (the descending branch of the HPG axis), so it is usually not reserved for the PCT phase. During the PCT phase, it is advisable to "activate" the upper branch (the hypothalamus/pituitary gland) with agents such as SERMs, when the testicles are preserved and ready to respond.

The most convincing evidence for the effect of this compound comes from a number of clinical experiments on healthy men with artificially suppressed LH/FSH secretion.

Coviello et al. (2005) demonstrated that even low doses of HCG (125–500 IU daily) are capable of maintaining intratesticular testosterone levels at near-physiological levels, despite complete gonadotropin suppression. This study provided key evidence of the effectiveness of HCG for the prevention of hypogonadism during AAS cycles.

Continuing these observations, Roth et al. (2010, 2011) conducted a series of studies demonstrating a dose-dependent response: increasing the HCG dose leads to a linear increase in intratesticular testosterone (ITT), but the effect is threshold-dependent — after a certain level, stimulation produces no increase. These data support the need for moderate doses and avoidance of overdose, consistent with practical regimens for athletes.

The human chorionic gonadotropin injection price remains relatively low, especially considering its importance in maintaining hormonal balance and overall well-being.

FAQ

How is HCG 5000 IU used in bodybuilding cycles?

HCG is used during anabolic steroid cycles to maintain natural testosterone production and prevent testicular atrophy. Typical use starts from week 4 of the cycle at around 1000 IU per week, split into two injections.

When should I start Human chorionic gonadotropin during a cycle?

It’s generally recommended to begin around week 4 of an AAS cycle once natural LH production starts to suppress, continuing until the end of the cycle.

Can HCG 5000 IU be used for PCT (Post Cycle Therapy)?

HCG is not usually recommended during PCT itself because it mimics LH. Instead, it should be stopped before PCT begins to allow SERMs (like Clomid or Tamoxifen) to restart the hypothalamic–pituitary–gonadal axis naturally.

Can Human chorionic gonadotropin be combined with Clomid or Tamoxifen?

Yes, but typically not at the same time. It is used before SERMs during the cycle or right before PCT. Combining all three simultaneously can cause desensitization of LH receptors. In our bundles section, you can also find human chorionic gonadotropin HCG for sale together with PCT products for convenient use.

Can HCG 5000 IU help with fat loss?

Indirectly, yes. By restoring healthy testosterone levels and supporting hormone balance, it may improve metabolism, energy, and lean mass retention, which together promote better body composition.