Clenbuterol is a beta-2 receptor agonist originally developed to treat asthma and other respiratory conditions.
Over time, it became popular in sports and fitness due to its fat-burning and thermogenic effects, as well as its ability to increase energy, focus, and endurance.
Unlike anabolic steroids, clenbuterol does not affect hormone levels, which makes it suitable for both men and women.
Main effects of Clenbuterol
🔥 Accelerates fat burning and increases metabolic rate
💨 Improves oxygen utilization and aerobic endurance
💪 Helps maintain muscle mass during calorie restriction
⚡ Increases energy, alertness, and motivation
💦 Reduces water retention and enhances muscle definition
🧠 Supports concentration and training focus
How to take Clenbuterol
Dosage and cycle
Clenbuterol is usually taken in short 2-week cycles to prevent receptor desensitization.
The dosage is gradually increased to allow the body to adapt.
Example scheme (2-week cycle)
Day
Dosage (mcg)
Notes
1
20
Start with a minimal dose to assess tolerance
2
40
Gradual increase
3
60
Noticeable thermogenic effect may begin
4
80
Moderate fat-burning phase
5
100
Near effective range for most users
6–12
120
Peak dose, maintain for one week
13
80
Begin tapering down
14
40
Finish the cycle, preparing for rest phase
After completing the 14-day course, take a 2-week break before starting the next cycle.
This pause helps restore beta-2 receptor sensitivity and maintain clenbuterol’s effectiveness in subsequent use.
Typical ranges:
Men: 120–140 mcg per day
Women: 80–100 mcg per day
Half-life: about 35 hours, so it’s recommended to take in the morning to avoid insomnia.
If needed, the daily dose can be divided into two intakes — morning and afternoon.
Combination use
Clenbuterol can be used:
With anabolic compounds during cutting phases to accelerate fat loss
With thyroid hormones (T3) or yohimbine for enhanced thermogenesis (advanced users only)
With taurine and potassium supplements to prevent muscle cramps and electrolyte imbalance
Possible side effects
Increased heart rate, tremors, and sweating
Insomnia and restlessness
Headaches and anxiety
Dry mouth and muscle cramps
Temporary rise in blood pressure
Nausea or dizziness at higher doses
Most side effects subside after lowering the dose or discontinuing use.
Exceeding recommended amounts increases the risk of cardiovascular strain.
How does Clenbuterol work?
Clenbuterol binds to beta-2 adrenergic receptors located in fat and muscle tissue.
This interaction activates adenylyl cyclase, which increases levels of cyclic AMP (cAMP) — a messenger that triggers fat breakdown (lipolysis).
Fatty acids released from adipose tissue are then used as an energy source, which accelerates fat loss.
Additionally, clenbuterol has a mild anticatabolic effect, helping preserve lean muscle mass during calorie restriction.
Its bronchodilating action also improves oxygen supply, which supports endurance and stamina during intense training.
Because of its effectiveness, clenbuterol is included in the World Anti-Doping Agency (WADA) Prohibited List, and should be used responsibly and within safe limits.
