Oxandrolone is a synthetic anabolic steroid first introduced in the 1960s.
It is derived from dihydrotestosterone (DHT), but modified to be less androgenic and more anabolic, which makes it one of the mildest and safest oral steroids available.
Originally created for medical use β including muscle wasting, burn recovery, and bone loss β it was later adopted by athletes for its ability to preserve lean tissue and enhance muscle tone during calorie restriction.
Unlike many other steroids, oxandrolone does not aromatize into estrogen, meaning users do not experience water retention, bloating, or gynecomastia.
Because of its mild nature, it is suitable for both men and women, especially in cutting or recomposition cycles.
Main effects of oxandrolone
πͺ Improves muscle definition and density
π₯ Promotes fat loss without muscle loss
βοΈ Increases protein synthesis and nitrogen balance
ποΈ Enhances strength and training endurance
π§ No aromatization or estrogen-related side effects
π§ Suitable for women and beginners due to mild androgenic activity
How to take oxandrolone
Administration
Route: oral, tablets taken with water
Frequency: 2β3 times per day to maintain stable blood concentration
Half-life: 9β13 hours
Dosage
Men: 30β50 mg per day (split into 2β3 doses)
Women: 10β20 mg per day
Typical cycle duration: 6β8 weeks
For cutting or body recomposition, oxandrolone is often combined with testosterone, drostanolone, or trenbolone.
After completing a cycle, a short PCT (post-cycle therapy) with clomiphene or tamoxifen is usually recommended to help restore natural hormone balance.
Possible side effects
Decreased appetite or stomach discomfort
Headache or mild nausea
Acne or oily skin (rare at moderate doses)
Temporary suppression of natural testosterone (mainly in men)
Unfavorable changes in cholesterol levels at high doses
Contraindications
Prostate or breast cancer
Severe liver or kidney impairment
Pregnancy or breastfeeding
Known hypersensitivity to anabolic steroids
How to store
Keep at room temperature (20β25 Β°C / 68β77 Β°F)
Protect from light and moisture
Store in the original packaging
How does oxandrolone work
Oxandrolone binds to androgen receptors in muscle tissue, activating anabolic pathways that enhance protein synthesis and nitrogen retention.
This leads to maintenance of muscle mass during calorie deficits and improved recovery between workouts.
Because it is a DHT-based compound, oxandrolone does not convert to estrogen β giving muscles a dry, hard, and defined appearance.
Additionally, it can slightly increase growth hormone levels and boost phosphocreatine synthesis in muscle fibers, supporting strength and endurance without significant water gain.
Thanks to its mild profile and strong anabolic effect, oxandrolone remains a popular option for cutting cycles, female athletes, and those seeking gradual physique improvement with minimal hormonal disruption.
