What is Cialyn (Tadalafil)?

Cialyn has a scientific name — tadalafil. It’s an effective medication that helps cope with erectile problems. It is primarily used to treat erectile dysfunction (ED) and benign prostatic hyperplasia (BPH). The medication belongs to a class of drugs known as phosphodiesterase type 5 (PDE5) inhibitors. Cialyn was approved by the FDA in 2003; since that time, it has become one of the most prescribed medications for ED.

Erectile Dysfunction Statistics

Erectile dysfunction is a common condition that affects a significant proportion of men worldwide. As recent statistics show, erectile dysfunction affects approximately 52% of men aged 40–70 years. This problem makes Cialyn a critical therapeutic. This tendency increases with age, affecting about 40% of men by age 40 and nearly 70% of men by age 70. This condition not only impacts the quality of life but also contributes to psychological stress, anxiety, and depression among affected patients.

BPH Statistics

In addition to ED, Cialyn is used to treat the symptoms of benign prostatic hyperplasia (BPH). The condition affects the prostate gland in men. Older men usually suffer from it, which is approved by studies. They show that about 50% of men aged 51–60 years and up to 90% of men older than 80 years experience symptoms of BPH. Symptoms include difficulty in urination, frequent urination, and urinary retention, which significantly impact the quality of life.

Usage and Popularity

Cialyn is available in various forms. Patients can take it daily or upon necessity. Thus, pills come as a versatile option for men with different lifestyles and needs. The daily version allows for spontaneous sexual activity without the need to plan ahead. Still, the as-needed version provides flexibility for those men who prefer to take medication only when required. Such flexibility acts in favor of the popularity and widespread use of Cialyn.

Mechanism of Action

PDE5 Inhibition

Cialyn regulates the inhibition of the enzyme phosphodiesterase type 5 (PDE5). The element is present in tissues, and the soft tissues of the penis are no exception. Phosphodiesterase type 5 is responsible for the breakdown of cyclic guanosine monophosphate (cGMP) in any organ. The component is an important ingredient of the drug, as it improves blood flow in the penis.

cGMP and Smooth Muscle Relaxation

The corpus cavernosum of the male penis releases nitric oxide (NO) when actively stimulated. The Cialyn component enhances the activity of the enzyme guanylate cyclase, which in turn increases the content of cGMP. This process leads to the relaxation of the soft muscle tissue of the penis, as the enzyme penetrates its cells. With powerful and strong blood flow, an erection occurs instantly. The medication counteracts the formation of the PDE5 component at the cellular level. As a result, the content of the cGMP component increases, and penis hardening due to intense blood flow naturally improves. This is the restoration of the organ’s sensitivity to erotic stimulation.

Extended Half-Life

One of the strongest advantages of Cialyn is that it’s not removed from the body very quickly. The duration of the half-life is almost a day — approximately 17.5 hours. This fact means that the activity of the active substances lasts much longer compared to PDE-5 inhibitors such as vardenafil and sildenafil. As a result, the activity of the active substance lasts up to 36 hours. In this regard, the medicine is called the “weekend pill”. When taking Cialyn, a man does not have to worry about the exact timing for a successful erection. Sexual activity is guaranteed throughout the weekend.